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| UWHC Lab Test Details | |
|---|---|
| Test Name | Monoclonal Protein Quantitation, Urine, 24 Hour |
| Test Code(s) | HCULCT, ULCT |
| CPT Code(s) | 84166, 84156 |
| Methodology | Gel Electrophoresis |
| Clinical Information | Urine protein electrophoresis is used to quantitate monoclonal light chain bands previously identified by urine immunofixation. |
| Testing Site | University Hospital |
| Days Performed | Mon-Fri, dayshift - day varies. |
| In-Lab Turnaround Time | 3 - 5 days. |
| Stat In-Lab Turnaround Time | Not available stat. |
| Collection Requirements | |||
|---|---|---|---|
| Specimen | 24 hour timed urine | ||
| Collection Container |
| ||
| Collection Instructions | No preservative necessary. For timed urine collections, collect all urine in container provided.
For 24-hour urine test the collection period must be within 22-26 hours. Collection period starts after first void of the period. It is very important to refrigerate specimen during and after the collection. Indicate the date and time collection started and date and time collection finished. If questions about collection process or container does not have instructions attached, call (608) 263-7060 for assistance. Patient instructions available at www.uwhealth.org. Search for 24-hour urine collection or UWH#4339. | ||
| Collection Volume | Entire collection | ||
| Specimen Processing Requirements | |||||||
|---|---|---|---|---|---|---|---|
| Stability |
| ||||||
| Sample Analyzed | Urine aliquot | ||||||
| Testing Volume | 10 mL | ||||||
| Pediatric Testing Volume | 10 mL | ||||||
| Specimen Processing | Refrigerate specimen. | ||||||
| Outreach Specimen Processing | Refrigerate specimen. Transport entire collection to UH Laboratory. | ||||||
| Specimen Transport | Immediately after specimen collection is completed, transport specimen to the laboratory. If transport is delayed, refrigerate specimen. | ||||||
| Unacceptable Criteria | Random urine collections. Urines with preservatives. Urines with bloody supernatants are acceptable but not desirable. Urines with no previously identified monoclonal proteins. | ||||||
| Interpretation | |
|---|---|
A written interpretive report with the scan is issued as a separate report. | |
| Test Limitations | The total urine protein method may underestimate the tubular and light chain protein fractions causing an underestimate in the semi-quantitative protein values reported by electrophoresis. The percent relationship of light chain proteins to tubular proteins and the ability to detect light chains is not affected. Monoclonal Protein Urine Electrophoresis requests more frequent than 14 days will automatically be cancelled by the laboratory system. |
| Additional Information | A professional fee is associated with this test. |
